Analysis of Wilms Tumors Using SNP Mapping Array-Based Comparative Genomic Hybridization
نویسندگان
چکیده
منابع مشابه
Analysis of Wilms Tumors Using SNP Mapping Array-Based Comparative Genomic Hybridization
Wilms tumor (WT) has been a model to study kidney embryogenesis and tumorigenesis and, although associated with hereditary, cancer predisposition syndromes, the majority of tumors occur sporadically. To analyze genetic changes in WT we have defined copy number changes and loss of heterozygosity in 56 Wilms tumors using high resolution oligonucleotide arrays at a average resolution of ~12 Kb. Co...
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ژورنال
عنوان ژورنال: PLoS ONE
سال: 2011
ISSN: 1932-6203
DOI: 10.1371/journal.pone.0018941